Q: What is NAD+, and why is it so critical to human health?
A: Nicotinamide adenine dinucleotide (NAD+) is a critical metabolite found in all human cells. It plays a key role in cellular metabolism within the “energy-producing factories” in every cell, the mitochondria. Mitochondria are organelles in a cell that act much like a digestive system: They bring in nutrients such as fats, proteins and carbohydrates, break them down, and convert them to energy. Researchers believe that mitochondria also play a role in protecting against many health problems.
One function of NAD+ in the body is to help the cell’s nucleus and its mitochondria communicate. Age or an unhealthy and sedentary lifestyle can lead to the decline of NAD+ in the body. In fact, as we get older our levels of NAD+ decline by as much as 50 percent. This can cause poor communication between the cell’s nucleus and mitochondria, slowing the production of energy. Because of this, we age more quickly. It’s a vicious cycle that contributes to many of the outward signs of aging.
Many problems can arise from a decline of NAD+ levels and the subsequent decrease in SIRT 1 and SIRT 3 enzymes (sometimes called longevity enzymes). They can include:
- vascular inflammation,
- increased fat storage,
- increased fat production and deposition,
- insulin resistance,
- fatigue and loss of muscle strength.
To avoid all of this physical degeneration, we need optimal levels of NAD+ in our bodies. But how do we increase our levels of NAD+? One way is to supplement with an NAD+ booster such as nicotinamide riboside (NR).
MitoBoost’s state-of-the art formula contains NIAGEN™, the first and only commercially available form of nicotinamide riboside (NR).